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CALM
Instant Relief Gel

How It Supports Your Skin

Calms

Relieves dry, itchy and irritated skin.

Moisturizes

Hydrates and supports skin barrier

Treats

Helps reduce redness and irritation

Clinically Proven Results

46 %
Reduction in overall atopic
dermatitis symptoms
(After 3 weeks)
73 %
Reduction in flare-up
area
(After 4 weeks)
100 %
Treatment
satisfaction

*Tested under dermatological supervision in three comprehensive clinical studies, using standard dermatological assessment measures, on individuals with atopic dermatitis.

Total participants across studies: 159 adults and children

Study 1: Tested on 30 subjects with mild to severe atopic dermatitis, evaluated by dermatologists using the SCORAD method.
Study 2: Tested on 30 children aged 2–12 with moderate atopic dermatitis, evaluated by dermatologists using the SCORAD method.
Study 3: Tested on 99 subjects (children and adults) with mild to moderate atopic dermatitis, evaluated using the Investigator Global Assessment (IGA) scale (0 = Clear to 5 = Very Severe).

Our Technology

Botaniplex® CALM is a botanical technology designed for dry, irritated, itchy, and redness-prone skin, including skin prone to atopic dermatitis. Its key actives provide prebiotic and antibiotic benefits, helping calm irritation, reduce redness, and support healthier, more balanced skin.

Add it to Your Skincare Routine

1

Cleanse

CALM Gentle soothing wash

2

Moisture

CALM Intense Moisture Cream

+

According To Needs

CALM Instant Relief Gel

Developed with Impact in Mind

Production

Manufactured in Italy in an environmentally certified facility

Box

100% FSC-certified paper sourced from responsibly managed forests

Tube

Made with recycled plastic

COSMOS

Formulated with COSMOS-approved botanical extracts